Some important information about Zoely (nomegestrol acetate and estradiol)
Many women explore the option of oral contraceptives for a range of reasons, including birth control, hormonal balance, family planning, and managing menstrual-related concerns. Zoely (nomegestrol acetate and estradiol) is an option when it comes to birth control pills, along with Micronelle 30 ED, Femme Tab ED 20 100, and other hormonal contraception options.
Understanding the importance of making informed decisions about medication, Chemist2U brings you this article, which aims to provide valuable information about Zoely (nomegestrol acetate and estradiol). Read on for more information about this hormone pill.
In this article

How does Zoely (nomegestrol acetate and estradiol) work?
Zoely (nomegestrol acetate and estradiol) is an oral contraceptive that combines two active ingredients: nomegestrol acetate (NOMAC) and estradiol (E2). Its main purpose is to provide effective contraception.[1]
The ingredient NOMAC is key in preventing ovulation, which means it stops the ovaries from releasing eggs.[2] In addition, NOMAC increases the thickness of the cervical mucus. Thicker cervical mucus is harder for sperm to travel through, which further improves pregnancy prevention.[3]
Estradiol is added to this combination to balance the levels of oestradiol, a natural hormone, which can be suppressed by contraceptive pills like NOMAC. By including estradiol, Zoely (nomegestrol acetate and estradiol) aims to maintain a more natural hormone balance.[4]
It’s important to note that while Zoely (nomegestrol acetate and estradiol) is primarily used for contraception, its suitability for an individual depends on various factors. If you’re considering Zoely (nomegestrol acetate and estradiol) – or any birth control pills like levlen ED and levonorgestrel and ethinylestradiol pills – as a contraceptive option, you should discuss it with your doctor.
How do you take Zoely (nomegestrol acetate and estradiol)
Taking Zoely (nomegestrol acetate and estradiol) involves a specific regimen to ensure its effectiveness as a contraceptive method. The pack contains twenty-four active tablets, followed by four placebo tablets.[5]
The recommended Zoely dosage is one tablet daily, starting with an active tablet on the first day of your menstrual cycle. The sequence is to first take the twenty-four white tablets, followed by the four yellow tablets. The packaging has stickers to help track the days of the week for each tablet.[6]
It is important to consult a doctor for personalised medical advice regarding the use of Zoely (nomegestrol acetate and estradiol).
Who can take Zoely (nomegestrol acetate and estradiol)
Before considering Zoely (nomegestrol acetate and estradiol), it’s advisable to have a comprehensive medical examination that includes a pap smear, a breast check, a blood pressure assessment, and a urine analysis. These tests are crucial in ensuring the suitability and safety of the pills for an individual.[7]
It is also essential for individuals to inform their doctor about any allergies they may have, particularly to foods, dyes, preservatives, or other medications.[8] This information helps the doctor determine if Zoely (nomegestrol acetate and estradiol) is appropriate for them.
Side effects of Zoely (nomegestrol acetate and estradiol)
Understanding the potential side effects of any medication is an important part of managing your health. Zoely (nomegestrol acetate and estradiol) is no exception. While some users of Zoely (nomegestrol acetate and estradiol) may not experience any side effects, others might. It’s important to be aware of them to make informed decisions.
Some of the common side effects that some users of this birth control pill experience include acne, the absence of menstruation, and breakthrough bleeding or spotting.[9] Other common side effects may include mood changes in general, headaches or migraines, nausea, breast pain, pelvic pain, and weight gain.[10]
Zoely (nomegestrol acetate and estradiol) and other medications
When considering Zoely (nomegestrol acetate and estradiol), a contraceptive pill, it’s important to be aware of its interactions with other medications.
Certain drugs can reduce its effectiveness, potentially impacting its ability to prevent pregnancy. These medications include those used to treat epilepsy, tuberculosis, HIV infections, and hepatitis C virus infection. Additionally, antibiotics and antifungals, as well as medicines prescribed for managing high blood pressure in the blood vessels of the lungs, can also interfere with its effectiveness.[11]
Medicines you should not use with Zoely (nomegestrol acetate and estradiol)
Several medicines used for treating epilepsy, such as phenytoin, primidone, barbiturates, carbamazepine, oxycarbamazepine, topiramate, and felbamate, may interfere with the function of Zoely (nomegestrol acetate and estradiol). Therefore, it is imperative that you speak with your doctor before taking a new medication or stopping your use of the ones you’re currently taking.[12]
Medications prescribed for tuberculosis, including rifampicin and rifabutin, can also impact its efficacy. This is similarly true for drugs used in the management of HIV infections, such as ritonavir, nevirapine, nelfinavir, and efavirenz, as well as medications for hepatitis C virus infection, like boceprevir and telaprevir.[13]
How to order Zoely (nomegestrol acetate and estradiol) through Chemist2U
At Chemist2U, we strive to make the process of obtaining your medications as convenient as possible. To begin, simply order delivery using this website or download the Chemist2U mobile app. Here, we offer the option for you to securely upload your eScript. This makes your prescription available to a local pharmacist, who will carefully prepare your medications before a dedicated courier delivers them to your door.
We understand that your needs may extend beyond prescription medications. That’s why we also offer a variety of over-the-counter medications and general pharmacy products, allowing you to conveniently add any additional items you want to your order.
Home delivery of prescription and over-the-counter medicines is just the beginning of how Chemist2U makes medication easy. We make it easy to keep all your scripts in one place so you are always on top of your medication. We’ll send you reminders when it’s time to reorder or get a new script.
Make your medication easy and have your medication delivered today!
References
[1] https://link.springer.com/article/10.1007/s40267-012-0005-9
[2] https://www.nature.com/articles/s41598-020-65642-5
[3] https://www.tga.gov.au/sites/default/files/auspar-zoely.pdf
[4] https://www.tga.gov.au/sites/default/files/auspar-zoely.pdf
[5] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf
[6] https://www.healthdirect.gov.au/medicines/brand/amt,112561000036101/zoely#howToTake
[7] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf
[8] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf
[9] https://link.springer.com/article/10.2165/11208180-000000000-00000
[10] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf
[11] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf
[12] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf
[13] https://www.nps.org.au/assets/medicines/58c21e41-fbc6-495b-a22c-a53300ff6060-reduced.pdf