Some information about vortioxetine
As part of a mental health wellness plan to treat major depressive disorder (MDD), a doctor may prescribe vortioxetine. If you or a loved one has been prescribed this mental health medication and you want to learn more about it, read on.
Chemist2U’s medical review team has broken down the basics, from its suggested dosage to interactions with other drugs. We’re here to make medication easier by providing useful information and home delivery across Australia.
In this article
How does vortioxetine work?
Similar to Cymbalta (Duloxetine) and Prozac (Fluoxetine), Vortioxetine is used to treat MDD. It is thought to work by blocking the serotonin transporter, enhancing the levels of serotonin, a key neurotransmitter in mood regulation. This psychiatric medication may directly and indirectly influence various neurotransmitter systems related to the neurobiology of MDD.[1]
How do you take vortioxetine?
It is a prescription antidepressant designed to be taken orally.
The vortioxetine dosage prescribed to an individual can vary depending on their age, the severity of their condition, and other factors. For adults under 65 years of age, Brintellix is usually taken at a daily dose of 10 mg. Your doctor may lower the dose to a minimum of 5 mg per day or increase it to a maximum of 20 mg per day. The starting dose is 5 mg taken once daily for elderly people 65 years of age or older.
It’s recommended that you take your medicine at about the same time each day to avoid missing a dose. Vortioxetine can be taken before or after meals. It’s recommended to swallow the tablets whole with a full glass of water.
As with many kinds of prescription medicine, it’s essential to store it in a cool and dry place, below 30 degrees Celsius. Typically, it has a shelf life of forty-eight months.[2]
Always follow the guidance of your doctor when taking any medication, especially those that are indicated for depression relief. Adjusting your dose or discontinuing use without professional advice can have serious consequences.
Who can take vortioxetine?
Vortioxetine is typically indicated for adults suffering from major depressive disorder, aiming to treat and prevent relapse. This serotonin modulator is not indicated for use in children.[3] It is recommended to only take vortioxetine during pregnancy if the risks outweigh the benefits.
Seek advice from a doctor if you are taking this medication and become pregnant, especially to discuss its suitability and any potential effects during pregnancy.
Side effects of vortioxetine
Similar to other mental health medications like Zoloft (Sertraline) and Zyban (Bupropion), vortioxetine can also lead to side effects such as changes in bowel habits, flu-like symptoms, decreased appetite, drowsiness, and itching. These side effects are generally mild to moderate, often arising in the first two weeks, and typically temporary.[4]
Remember, the most common side effects, like nausea, headaches, and dizziness, are usually manageable.[5] Additionally, research has also shown that individuals taking vortioxetine experience an increase in weight.[6]
If you experience any side effects that concern you, it’s crucial to inform your doctor promptly.
Vortioxetine and other medications
If taking vortioxetine, it’s crucial to be mindful of potential interactions with other medications. Certain drugs, particularly those affecting serotonin levels like SNRIs, SSRIs, TCAs, and others such as triptans, MAOIs, and some pain relievers, should be avoided. Also, be cautious with over-the-counter products like St. John’s Wort and dextromethorphan due to their serotonergic effects.
This medication can also increase the risk of abnormal bleeding, especially when taken with medications that influence blood clotting, such as naproxen, warfarin, and aspirin. Users should keep an eye out for any abnormal bleeding symptoms.
Medicines you should not use with vortioxetine
Be aware of the heightened risk of serotonin syndrome, a serious condition, when combining vortioxetine with other medications that increase serotonin levels.
Importantly, it is contraindicated with monoamine oxidase inhibitors (MAOIs), another type of medication for depression. The contraindication remains even if vortioxetine is stopped if MAOIs are prescribed within three weeks.[7] Examples of MAOIs include tranylcypromine and phenelzine.
Only your doctor can lay out your specific medication schedule relating to this medication.
How to order vortioxetine through Chemist2U
Ordering your prescription medication with Chemist2U is simple and stress-free.
First, download our app or navigate this website to start your order. Easily upload your prescription and browse our wide selection of over-the-counter goods to add to your cart. Rest assured, a qualified chemist from your local community will carefully fill your order.
Same-day delivery is available with the majority of medications; simply ensure that you place your order before the cutoff time. This is typically 2.00 p.m., but cutoff times may vary in some locations. There are a few products (such as Ozempic and Mounjaro) that are delivered by AusPost. Please allow five to seven business days for these medications to be delivered.
Order home delivery at Chemist2U today!
References
[1] https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.824831/full
[2] https://media.healthdirect.org.au/medicines/GuildLink_Information/203986/CMI/lucbrint10322.pdf
[3] https://www.healthdirect.gov.au/medicines/brand/amt,712621000168109/brintellix
[4] https://www.nps.org.au/assets/medicines/acfe143b-c1bd-4369-bd9e-a53300ffafb7.pdf
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296590/
