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Saxenda vs Wegovy (semaglutide): the discussion between these two prescription weight management medications calls for more information about their similarities and differences, regarding their dosage guidelines, side effects, interactions and more. 

With this, the medical review team at Chemist2U is here to provide helpful insight through a Wegovy vs Saxenda comparison. Read on to get more insights that can guide your discussion with your GP to decide whether one of these is suitable for you.

In this article

How does Saxenda vs Wegovy (semaglutide) work? 

Both Saxenda (liraglutide) and Wegovy (semaglutide) belong to a class of medications known as GLP-1 receptor agonists. These GPL-1 medications work by stimulating the pancreas to release insulin and suppressing glucagon levels, both of which help control blood sugar in the body.

These medications, along with other alternatives to Wegovy and Saxenda (liraglutide), may also be prescribed as weight loss medication that works by suppressing your appetite. They’re also thought to work by helping decrease hunger and control food consumption for weight loss.1

How do you take Saxenda vs Wegovy (semaglutide)?

When it comes to comparing Saxenda vs Wegovy (semaglutide), it’s also crucial to understand differences in how they’re administered. 

Wegovy (semaglutide) is taken through a subcutaneous injection typically once a week, with doctors gradually increasing the Wegovy dosage over time, which typically allows the body to adjust.2 

On the other hand, Saxenda (liraglutide) requires a commitment to daily self-administered injections, usually taken at the same time each day with similar progressive dosage increases.3 

As for the administration sites, both prescribed weight loss injections are generally carried out at the abdomen, thigh or upper arm. Additionally, based on manufacturer specifications, these drugs are to be kept refrigerated to maintain their integrity but brought to room temperature before deployment. 

On top of all these Saxenda vs Wegovy (semaglutide) points, keep in mind that your doctor may recommend more specific instructions depending on your unique circumstances. 

Who can take Saxenda vs Wegovy (semaglutide)? 

Doctors typically prescribe Wegovy for weight loss, particularly for adults who have a BMI of 30 or higher, classified as obese or for those with a BMI of 27 or higher with at least one weight-related condition such as hypertension or type 2 diabetes.4

In comparison, Saxenda (liraglutide) can also be prescribed to a group of patients that fit within similar BMI categories and weight-related conditions: a BMI of 30 or more or a BMI of 27 or more with a weight related health problems, like diabetes and high blood pressure.5 

Aside from this, as GLP-1 receptor agonists, doctors may advise against the use of Wegovy (semaglutide) and Saxenda (liraglutide) for individuals with a history of medullary thyroid cancer or specific types of pancreatitis. Neither medication should be used by breastfeeding or pregnant women. Both medications are indicated to be used in conjunction with increased physical activity and a reduced-calorie diet. 

Side effects of Saxenda vs Wegovy (semaglutide)

Understanding the Saxenda vs Wegovy (semaglutide) discussion also means learning about the common Saxenda (liraglutide) and Wegovy side effects. Patients often experience nausea, vomiting, diarrhea, constipation and general gastrointestinal discomfort when starting these medications.

Most gastrointestinal side effects generally happen within the first month of treatment.6 During this period, the body usually acclimates to the new medication. While the side effects tend to be prominent early on, they typically diminish as the body becomes familiar with the medication. 

Saxenda vs Wegovy (semaglutide) and other medications

When it comes to the Saxenda vs Wegovy (semaglutide) discussion and topics like ‘What is Wegovy (semaglutide)?’ remember that these prescribed obesity management medications are thought to slow down gastric emptying. As such, both Saxenda (liraglutide) and Wegovy (semaglutide) can potentially influence how the body absorbs oral medications, necessitating doctor-guided changes in dosages.7 8 

Above all, it’s essential to inform your doctor about all medications being taken. In doing so, interactions with medications that require precise timing and absorption – such as blood thinners or heart medications – can be thoroughly evaluated. 

Medicines you should not use with Saxenda vs Wegovy (semaglutide)

Whether you’re comparing Saxenda vs Wegovy (semaglutide) or just trying to address safety concerns, take note that your doctor will likely advise against using either of these medications with other GLP-1 receptor agonists. This is because such a combination typically amplifies the adverse side effects without anything else added.

In addition, using insulin, sulfonylureas or glinides with these medications requires caution and guidance from your doctor. These drugs are also thought to work by managing blood sugar levels, but when taken alongside Saxenda (liraglutide) or Wegovy (semaglutide), they might increase the likelihood of hypoglycemia.9 10 Prescribed adjustments may be necessary when these drugs affect blood sugar. 

Ultimately, doctors play a critical role in assessing the impact and making appropriate dosage changes to help ensure that treatments remain suitable without introducing new issues. 

How to order home delivery of Saxenda vs Wegovy (semaglutide) with Chemist2U

Chemist2U is dedicated to making your medication easy and helping you stay on top of your medication. Start by downloading our app or simply using our website. Here’s a brief overview of how to use our service:

  • Add your prescriptions. Uploading your eScript is a breeze – simply follow the prompts! We will store your prescriptions in My Scripts, Chemist2U’s script wallet. That way your scripts will always be safe and easy to find, plus you will get handy reminders when it’s time to reorder!
  • Add any over-the-counter medications and general pharmacy goods. Alongside your prescription medications, you can select from a wide range of over-the-counter medicines and general pharmacy products, just as if you were in a physical pharmacy.
  • Your prescriptions are in good hands. A qualified partner pharmacist will handle your order with care.
  • Direct to your door. We deliver to any address in Australia! To see all our delivery options, click here

For any queries related to your order, use the web chat service bottom right on this customer support page. Our team are here to help.

 We’re making medication easy right across Australia! So why not have your medications delivered by Chemist2U today.

References

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC4119845/

2.  https://www.wegovy.com/taking-wegovy/how-to-use-the-wegovy-pen.html 

3.  https://www.saxenda.com/about-saxenda/dosing-schedule.html 

4.  https://www.proquest.com/openview/c6bc12a5659ab13cb9b27093c0d8c753/1?pq-origsite=gscholar&cbl=136155 

5.  https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2016-CMI-01009-1 

6.  https://pubmed.ncbi.nlm.nih.gov/36568085/ 

7.  https://www.goodrx.com/victoza/interactions 

8.  https://www.goodrx.com/wegovy/interactions 

9.  https://www.goodrx.com/victoza/interactions 

10.  https://www.goodrx.com/wegovy/interactions 

Please Note: Chemist2U does not endorse or promote the therapeutic benefit of any medication. Any decision to administer a therapeutic good should be taken in consultation with your doctor.

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